PQQ (Pyrroloquinoline quinone) and CoQ10 are both essential for good health. They are natural antioxidants and help the body produce energy. They are also thought to be protective against degenerative conditions.

Pyrroloquinoline quinone is an antioxidant that helps protect the brain. Its effects include improving memory, sleep, and vigor. It also improves brain function in older people. The compound can even repair damage caused by strokes and cancer.

CoQ10 is also thought to have beneficial effects on the heart. It increases the creation of new mitochondria and helps protect the mitochondria from oxidative damage. It also helps support the electron transport system in mitochondria. In addition, it may enhance endurance performance in athletes.

It is thought that high-dose supplementation of coq10 is beneficial for those suffering from Parkinson’s disease. It has also been suggested to increase liver enzymes. However, the effect of coq10 on endurance athletes has not been studied.

The antioxidant effects of pyrroloquinoline quinone and coq10 are believed to be synergistic. This means that both compounds work together to improve the brain’s memory and vigor. They also have potential to increase metabolic rate and increase antioxidant defense.

Several studies have shown that people who supplement with PQQ and CoQ10 are able to perform better on memory tests. In addition, both compounds have been found to improve sleep.

There is also a link between low coq10 levels and chronic diseases. It is thought that the reduction of coq10 in the bloodstream may affect the expression of lipopolysaccharide-sensitive genes.