NAD+ is an essential coenzyme for metabolism and aging. The reduction of NAD+ levels is one of the main contributors to age-related diseases. NMN is a metabolite of vitamin B3, and it is believed that supplementation may provide neuroprotective effects.
Studies on NMN have focused on its health benefits for Alzheimer’s disease, cardiovascular disease, and age-related type 2 diabetes. However, it is important to note that the safety of high doses has not been assessed.
The scientific community is still working to understand NMN’s anti-aging effects. However, the effects have been demonstrated in various animal studies. In addition, NMN has been found to enhance insulin sensitivity, exercise endurance, and physical performance.
Scientists are also researching the potential benefits of NMN for skin. According to researchers, NMN supplementation is beneficial in preventing and treating age-related conditions that affect the skin.
NMN has been found to reduce oxidative stress. Oxidative stress is caused by chronic inflammation. These inflammations accelerate the breakdown of the body’s own NAD+. As a result, energy production in the mitochondria is reduced.
NMN has also been found to be effective in protecting against the negative effects of age-related changes in haemoglobin. Its effect on cardiovascular function is predicted to be mediated by anti-inflammatory and anti-apoptosis genes.
NMN has been marketed as a functional food. Some vendors claim that their products contain 500 mg of NMN. Others claim that their products contain 250 or 125 mg.
Although there are many NMN-based supplements in the market, there is no conclusive proof that they are safe. Therefore, proper clinical investigations are needed to assess the efficacy and safety of NMN.