Pyrroloquinoline quinone (PQQ) is a natural compound that is found in many types of leafy vegetables, and it’s a powerful antioxidant. This antioxidant plays a vital role in the body, as it helps fight free radicals. Free radicals are toxic by-products of the body’s metabolism. As a result, free radicals can damage a wide range of cells, leading to chronic diseases.
PQQ is a coenzyme that is essential for mitochondrial energy production. Its mechanism involves a variety of factors, such as mitochondrial biogenesis and cell signaling pathways.
PQQ has been shown to have a positive effect on cognitive function, and in some cases it’s also been shown to have a neuroprotective role. However, the extent of its benefits on human health is still unknown.
While it’s believed that PQQ plays a role in brain health, there aren’t a lot of clinical studies. There are some promising findings, however.
Some of the most intriguing of these are the results of a study in leukemia cells. The study shows that PQQ is an antioxidant that can help protect cancer cells from damage. In addition, PQQ may have an antiinflammatory role.
Researchers have found that the supplementation of PQQ can enhance mitochondrial function in otherwise healthy humans. Using a crossover design, researchers studied the effects of PQQ on mtDNA and oxidative metabolism in 10 subjects.
During the course of the study, plasma and urine PQQ levels were measured. Compared to the control diet, the dietary PQQ group experienced a reduction in urinary concentrations of some key metabolites.