A few anti aging pills that work in people are available on the market, but are they really as effective as they claim to be? Most supplements contain a low dose of ingredients and have not been tested in humans.
Many people think that taking extra antioxidants will slow down aging, but this is unlikely to happen in most healthy individuals. In fact, studies have found that suboptimal levels of antioxidants increase the risk of aging-related diseases.
One way to slow aging is to avoid toxic chemicals that damage body tissues. Environmental toxins are one source of this deterioration. Another major cause is chronic inflammation. It is believed that reducing chronic inflammation will help slow aging. There are several ways to decrease aging-related inflammation, including eating berries packed with flavonoids and taking small amounts of drugs like carnosine.
Senolytic drugs have been shown to clear out senescent cells, which are aging cells that secrete toxic factors. These cells disrupt biological pathways, contributing to osteoarthritis, cognitive impairment, and other problems. Clearing out senescent cells can improve lung and kidney function, increasing the body’s resilience. This means that the body is more resistant to aging-related illnesses, and may even be able to extend the lifespan of the elderly.
The National Institutes of Health’s Interventions Testing Program (ITP) is conducting a quiet trial of compounds that are designed to extend longevity in mice. Three major laboratories across the nation have participated in the study.
Several popular “anti aging” supplements have been tested in animals, but have not been scientifically proven to extend lifespan. Green tea extract, rapamycin, curcumin, and glucosamine sulfate have been examined. However, all three of these ingredients did not prove to extend the lifespan of the animals.
There are also many popular “anti aging” supplements that have been tested on a cellular level, but not in humans. For example, acarbose and simvastatin were both shown to shorten the lifespan of male mice, but not females.
Senolytic agents also have been studied in humans, and early data suggest they may be able to slow aging. However, the results have been mixed.
Senolytic agents are thought to be effective because they kill senescent cells, which are believed to contribute to many of the diseases associated with aging. While it is possible that these agents will eventually be used to treat human diseases, there is still much work to be done before they are considered a safe and effective treatment.
In addition to senolytics, there are other drugs that are being investigated for aging. Some are known to be useful, but they are either made prescription-only or have complex risk profiles.
Scientists are looking into ways to break cross-linked proteins that are associated with aging. They are also looking at ways to break down AGEs, which are a type of protein that is believed to contribute to the aging process. AGEs are found in most tissues in the human body, and they increase with age.