Nicotinamide mononucleotide (NMN) is a molecule that is naturally present in a variety of food sources, and it plays an important role in the body’s ability to maintain a normal level of NAD. It is a precursor of NAD, which helps the body to produce energy. As the human body ages, NAD levels decrease, which results in reduced cell function and increased cell death.
NMN supplements have been studied for their potential to enhance human health. Several studies have shown benefits including improved cardiovascular and muscle function, as well as increased insulin sensitivity and insulin signaling.
However, there are not many published clinical studies on the effectiveness of NMN. It is not yet classified by the FDA as a GRAS (Generally Recognized as Safe) supplement. This is due to a lack of toxicological data.
In order to be considered a dietary supplement, NMN has to undergo postmarket regulatory inspections by the Food and Drug Administration. Some studies have suggested that NMN may improve heart and bone strength, as well as prevent certain neurological disorders like Alzheimer’s disease.
NMN supplementation also increases the levels of NMN byproducts in the blood. Supplementation has been found to reduce the death of neurons and other brain cells, which is thought to contribute to better physical and mental health.
Studies have shown that NMN supplements may also be beneficial in reducing oxidative stress, insulin resistance, and neuroinflammation. They have also been associated with improved insulin sensitivity and muscle responsiveness in older people.