Nicotinamide mononucleotide, also known as NMN, is a precursor to the chemical NAD+, a coenzyme that helps your body generate energy. The molecule is involved in many critical functions in your body, including your heart, your eyes, and your brain.
When you take NMN you will experience a range of benefits, from improved cardiovascular fitness to a better overall mood. Taking NMN daily may also help you avoid becoming diabetic.
In mice, NMN increases the activity of the gene SIRTUINS, which has been called the “skinny gene.” It is responsible for preventing the breakdown of DNA and combating oxidative stress. NMN has been found to increase the activity of this gene in the liver and the heart.
A study conducted at the University of Tokyo found that NMN helped to restore muscle function in older men. NMN may also improve the quality of sleep. However, more clinical trials are needed to determine the safety of NMN in humans.
The most recent rodent studies are using dosages of 300 mg per kilogram of body weight. These dosages are much higher than what is prescribed for humans.
A second study looked at the effects of NMN on the cardiovascular system of postmenopausal women. Twenty-six runners of ages 27 to 50 were given NMN during an exercise test. Results showed that NMN reduced body weight by up to 10%.
While there is a lot of research on NMN and its role in aging, there is still much more research to be done. Some scientists believe that NMN can slow the aging process by extending the length of telomeres, which are the ends of chromosomes.