Pyrroloquinoline quinone (PQQ) is a redox cofactor that is found in the body. It is an antioxidant, which means that it neutralizes free radicals and reduces oxidative damage. In addition, it promotes the growth of new mitochondria, which is a key function of cells. PQQ helps maintain cellular energy and supports cognitive and heart health.
Aside from being an antioxidant, PQQ also has the ability to protect against damaging proteins. For example, it inhibits the synthesis of amyloid proteins associated with Alzheimer’s disease. Other studies suggest that it has neuroprotective properties. However, further research is needed.
PQQ has also been shown to increase metabolic flexibility in obese mice offspring. This is because it stimulates the synthesis of nerve growth factor FCN. These factors are essential for neuron health.
Animal studies have also shown that PQQ may protect the heart. An experiment conducted with animals after a heart attack revealed that administration of the compound reduced the size of damaged areas. The test showed that the molecule also protected the heart from the oxidative stress of an acute heart attack.
It was also noted that PQQ augmented the ability of a cell to carry out the redox cycle. It was found that cells treated with the supplement before they were exposed to hydrogen peroxide restored their respiratory capacity.
Studies have suggested that PQQ may be beneficial in age-related cognitive decline. One study showed that PQQ increased memory tests. Another study suggests that it has the ability to strengthen brain cells, promoting the development of Schwann cells.